In rapidly urbanizing developing countries, the prevalence large-scale informality within urban economies increases social vulnerabilities, stifles worker productivity and dampens regional economic growth. With the prospect of better jobs attracting millions into cities each year, rising urban poverty levels are encouraging international nonprofits to allocate greater resources toward urban programs. Our fieldwork in Pakistan reveals that above all else, urban informal workers require improvements in public service delivery, skillset development and collective bargaining capacity. We propose implementing future urban programs through an iterative learning, adaptation and implementation approach allowing nonprofits to leverage greater impact from finite resources.