This independent assessment of the What Works Collaborative (WWC) was conducted in the summer and fall of 2012 and focused on determining the benefits, the challenges, and the influence of the WWC. The assessment included 21, one-hour, key informant interviews with WWC participants. Respondents were questioned about the management of the collaborative and research development processes, the efficiency of the collaborative model, the overall quality and relevance of the research, and the dissemination strategies.