Public agencies, at all levels, increasingly rely on nonprofit organizations to address social issues and deliver publicly funded human and cultural programs and services. Therefore, strengthening relationships between nonprofits and government is essential to enhancing the quality of service delivery. This brief provides information and insights on the nonprofit-government contracting and grants relationships in Prince George's County, Maryland. The findings convey challenges administering government grants and strengthen the need for local government policymakers to strategize with their nonprofit and government partners about how to better align their efforts to address specific problems and improve nonprofit-government relations.