This report describes results for participants in the second round of the Health Profession Opportunity Grants Program (HPOG 2.0) from the beginning of the Program through the end of Year 2. HPOG encourages grantees to design and implement their programs to include basic skills education and to employ career pathways strategies. This report provides information on the types of trainings, activities, and support services offered, the characteristics of those enrolled, their participation in different activities, and receipt of services. It also describes participant outcomes including completion of basic skills and healthcare training, receipt of certifications and degrees, progression from entry-level to higher-level training, and employment in healthcare jobs.