Residential instability can disrupt employment, finances, health, education, social networks, and more. And yet, too little policy attention has been devoted to the issue. States and localities have critical roles to play in creating integrated solutions to a complex challenge, but to date, their strategies have largely been confined to specific sectors and institutions, when more cross-cutting and holistic approaches are needed. This brief details steps that states and localities can take in several areas, including affordable housing, education, law, health, and human services, to minimize the occurrence or mitigate the consequences of residential instability.