The share of low-income single mothers disconnected from work and TANF ranges from 20 to 25 percent. Most disconnected low-income single mothers experience barriers to work and most of their families live in poverty. This brief reviews what we know about the numbers and characteristics of disconnected mothers, their economic well-being, their living arrangements, and the length of time that they tend to be disconnected. The brief draws lessons for policy, including efforts for keep TANF recipients in great need from losing TANF benefits and becoming disconnected and to improve employment prospects for those with serious challenges to work.