This handbook outlines strategies to help juvenile probation practitioners align policy and practice with research to promote better outcomes for their agencies and youth. It addresses key implementation tasks that can help probation agencies prepare to transition to – or more fully implement – a research-informed approach, integrate that approach throughout their systems and culture, and sustain the change for the long-term. Reflection questions, publicly-available tools, and real-world examples are included to help practitioners bring research-informed practice to life.