The purpose of the study was to construct a methodology to identify and describe community organizations and networks that strengthen families and children in three low-income neighborhoods in Washington, D.C. The study involved developing tools to analyze the size, scope, and structure of community organizations that foster local leadership and leverage resources on behalf of families and children. A spatial analysis was undertaken to understand the relationship between the nonprofit infrastructure and socioeconomic characteristics of the studied neighborhoods. Also included is a description of community-based groups and networks that enhance the well-being of families and children.