Many low-income adults have a health problem or impairment that limits their ability to participate in work. This brief examines the employment and program participation patterns of low-income adults with disabilities, and how well the current safety net meets their needs. Using data from the third round of the National Survey of America's families, the findings question current benefits and services, as many will likely lead to a lifetime of support rather than to a job. The employment rates of those with disabilities are much lower than among other low-income adults.