This report assesses the administrative, fiscal, and political feasibility of implementing a universal childhood vaccine purchasing program in New York State. Program benefits, stakeholder impacts, and implementation challenges were considered through interviews with key stakeholders, program managers in states with universal vaccine purchasing programs, and independent experts. Costs were estimated from population data, immunization schedules, and a range of possible purchase prices. Findings illustrate that a universal vaccine purchasing program is feasible in New York and could result in benefits for children and primary care providers, but ought to build upon existing infrastructure and incorporate lessons from other states' experiences.