Like most cities, New York City counts on government, business, and nonprofit organizations to work together to create supportive, safe, and productive environments. Although building and sustaining effective partnerships can be mutually beneficial, it is seldom easy to achieve. This brief describes how New York City government and area nonprofits worked together to build meaningful partnerships and collaborations during Mayor Michael Bloombergs administration while strengthening the capacity of nonprofit agencies. This brief is one in a series examining selected social service initiatives undertaken during the Bloomberg administration.