Organizations of all types are forming partnerships--including with organizations outside their fields--to help them carry out their missions. The arts are no exception: many are working with agencies not primarily devoted to the arts to accomplish their artistic and community service goals. These partnerships are not easy to forge or maintain, however, and involve real risks to reputations, constituent relations, organizational missions, and investments of time, money and talent. Fortunately, important practical lessons are emerging to help groups identify and reduce these risks. This brief presents some of these lessons.